Andrews–Paulos Research & Education Institute: Clinical Trials
APREI provides the oversight, staff and support for the implementation of clinical studies that keep our physicians on the cutting–edge of medicine.
These studies provide patients the latest technological advancements in pharmaceuticals and medical devices and aid both physicians and patients in making better informed treatment decisions. These studies impact the clinical outcomes for patients as our findings are shared with clinicians throughout the world.
Current Clinical Trials At Andrews–Paulos Research & Education Institute
| Name |
AOSSM–Association of Orthopedics and Sports Medicine Association |
| Description |
A national survey of youth baseball pitchers regarding pitching exposure and elbow and shoulder problems |
| Investigator |
Juliet M. DeCampos, M.D. |
| Discipline |
Orthopaedics & Sports Medicine |
| Target Disease |
Youth Baseball Pitchers in the Community and Surrounding Communities |
| Name |
AOSSM–Association of Orthopedics and Sports Medicine Association |
| Description |
Association among pitching variables, elbow or shoulder injuries, and structural arm differences in youth baseball pitchers seen in the clinic |
| Investigator |
Juliet M. DeCampos, M.D. |
| Discipline |
Orthopaedics & Sports Medicine |
| Target Disease |
Youth Baseball Pitchers in the Community and Surrounding Communities |
| Name |
BREG |
| Description |
Investigation of the subjective effects of the use of two non–invasive modalities in the treatment of symptomatic medial compartment OA of the knee |
| Investigator |
Roger V. Ostrander, M.D. |
| Discipline |
Orthopaedics |
| Target Disease |
|
| Name |
CAIS |
| Description |
A Multicenter, Randomized, Pivotal Study to Evaluate the Safety and Efficacy of the Cartilage Autograft Implantation System (CAIS) for the Treatment of Articular Cartilage Lesions of the Knee |
| Investigator |
Charles A. Roth, M.D. |
| Discipline |
Orthopaedics |
| Target Disease |
Cartilage Defects in the Knee |
| Name |
FIDIA |
| Description |
Multi–center, Parallel, Double–blind, Blinded Evaluator, Randomized, Placebo–controlled Study to Evaluate the Efficacy of a New Viscoelastic Hydrogel (HYMOVIS™) in the TX of Knee Osteoarthritis with an Open–label Extension |
| Investigator |
Charles A. Roth, M.D. |
| Discipline |
Orthopaedics |
| Target Disease |
|
| Name |
IL Pharma |
| Description |
Randomized, Multi–center Double–blind, Placebo–controlled Phase III Trial to Evaluate the Efficacy,Tolerability & Safety of MRX–7EAT Etodolac–Lidocaine Topical Patch in TX of Ankle Sprains |
| Investigator |
Joshua G. Hackel, M.D. |
| Discipline |
Orthopaedics & Sports Medicine |
| Target Disease |
|
| Name |
In–House Research |
| Description |
Prospective study to determine the incidence of simultaneous cervical neuropathies in patients who have undergone arthroscopic rotator cuff repair |
| Investigator |
Joseph Bellapianta, M.D. |
| Discipline |
Orthopaedics |
| Target Disease |
Post–surgical Rotator Cuff Repair |
| Name |
In–House Research |
| Description |
Prospective study for the incidence of phrenic nerve palsy during a posterior approach to the brachial plexus using ultrasound guidance when performing regional anesthesia prior to scheduled outpatient shoulder surgery |
| Investigator |
Gregory V. Hickman, M.D. |
| Discipline |
Anesthesia / Pre–surgical anesthesia |
| Target Disease |
Analgesia |
| Name |
ORTHOVISC |
| Description |
A comparison of Orthovisc® to corticosteroid injection in shoulder osteoarthritis: Orthovisc® randomized clinical tria |
| Investigator |
Charles A. Roth, M.D. |
| Discipline |
Orthopaedics |
| Target Disease |
Shoulder Osteoarthritis (OA) |
| Name |
Stryker Triathlon |
| Description |
The Triathlon PKR Unicondylar Knee System Outcomes Study |
| Investigator |
Brett R. Smith, M.D. |
| Discipline |
Orthopaedics |
| Target Disease |
|
| Name |
Stryker Tritanium |
| Description |
A Prospective, Post–market, Multi–center Study of the Tritanium® Primary Acetabular Shell |
| Investigator |
Brett R. Smith, M.D. |
| Discipline |
Orthopaedics |
| Target Disease |
|
| Name |
VIRGO |
| Description |
Variation in recovery: Role of gender on outcomes of young acute myocardial infarction (AMI) patients |
| Investigator |
Thahn Duong–Wagner, M.D. |
| Discipline |
Cardiology |
| Target Disease |
Women, aged 55 years and younger, who experience an acute heart attack |
| Name |
ZYMOGENETICS |
| Description |
A phase 4, open–label, single–group immunogenicity and safety study of re–exposure to Recothrom® (r thrombin) in surgical hemostasis |
| Investigator |
Layne R. Yonehiro, M.D. |
| Discipline |
Vascular Surgery |
| Target Disease |
Patients with prior surgical exposure to Recothrom® |